Treatment Options

Preimplantation Genetic Testing

Preimplantation Genetic Testing (PGT) is a technique used in In-Vitro Fertilization (IVF) which allows genetic evaluation of an embryo before transfer.

Preimplantation Genetic Testing

Preimplantation Genetic Testing (PGT) is a technique used in In-Vitro Fertilization (IVF) which allows genetic evaluation of an embryo before transfer. PGT optimizes embryo selection that could provide the best chance of implantation and successful pregnancy. This technique involves the sampling of cells from an embryo (blastocyst). The cell is cultured and analyzed for genetic abnormalities. Embryos will then be frozen immediately after biopsy for preservation. Results are usually available within 7-10 days.

Preimplantation Genetic Testing

Preimplantation Genetic Testing (PGT) is a technique used in In-Vitro Fertilization (IVF) which allows genetic evaluation of an embryo before transfer. PGT optimizes embryo selection that could provide the best chance of implantation and successful pregnancy. This technique involves the sampling of cells from an embryo (blastocyst). The cell is cultured and analyzed for genetic abnormalities. Embryos will then be frozen immediately after biopsy for preservation. Results are usually available within 7-10 days.

Types of PGTs

PGT-A

PGT-A is a standard genetic testing that evaluates the matching sets of chromosomes, including gender. This testing can identify if the individual has any extra or missing chromosomes, known as aneuploidy, and can prevent the risk of a child with abnormalities such as Down Syndrome.

PGT-M

PGT-M is a testing that looks for a specific single gene defect, such as cystic fibrosis. This is normally performed for individuals who are known carriers and/or have a family history of a specific inheritable disorder. Additional family testing and evaluation is needed prior to the embryos being tested.

PGT-SR

PGT-SR is used when the couple has known chromosomal rearrangements, such as translocations and inversions. This can prevent patients from giving birth to a child that may have extra or missing genetic materials, which may have led to pregnancy loss.

 

Other patient groups that may benefit from PGT include recurrent pregnancy loss (RPL), increased reproductive age of the female partner, repeated implantation failure (i.e. multiple failed IVF cycles).